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Warum ein Wachstumshormon-Test wichtig ist



Das Wachstumshormon (GH) spielt eine zentrale Rolle bei der Zellteilung, Gewebereparatur und dem Stoffwechsel. Unzureichende oder übermäßige GH-Werte können zu Wachstumsverzögerungen, metabolischen Störungen und anderen Gesundheitsproblemen führen.






Typische Symptome einer GH-Störung



Symptom Hinweis auf Unter- / Überschuss


Verlangsamtes Wachstum (bei Kindern) Mangel an GH


Gewichtszunahme in der Taille, Bauch oder Oberarme GH-Mangel bei Erwachsenen


Schmerzen in Gelenken und Muskeln Mangel an GH


Erhöhte Triglyceride und Cholesterin Mangel an GH


Körperbehaarung reduziert (bei Frauen) Mangel an GH


Übergewicht, Fettverteilung im Bauchbereich Überproduktion von GH


Hautprobleme (Alopecia, Hirsutismus) GH-Überschuss bei Erwachsenen



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Diagnoseverfahren



a) Anamnese & körperliche Untersuchung


Messung von Körpergröße, Gewicht und BMI.


Analyse der Körperproportionen (z.B. Schulterbreite, Taillenumfang).



b) Bluttests


Basal-GH-Spiegel: Am Morgen (7–9 Uhr) ohne Stimulation messen.


Insulin-Resistenz-Marker: HbA1c, FPG.


Leberfunktionstests: AST, ALT.



c) Stimulierungstest


Glukose-Stimulierungstest (IGTT): 0.75 g/kg Körpergewicht Glukose oral oder intravenös; GH-Messung alle 30 Minuten für 2–3 Stunden.


Gonadotropin-Stimulationstest: hCG oder GnRH in Kombination mit GH-Messungen.



d) Bildgebung


Magnetresonanztomographie (MRT) der Hypophyse, um Tumoren zu identifizieren.








Interpretation der Ergebnisse



Test Typischer Wert bei Mangel Typischer Wert bei Überschuss


Basal-GH

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